Abstract
Human immune function is shaped not only by genetic and biological factors but also by a wide range of environmental and lifestyle influences. Rapid urbanization, changing dietary habits, sedentary behavior, and increased exposure to environmental pollutants have significantly altered immune health in modern populations. These factors can either strengthen immune defenses or impair immune regulation, thereby influencing susceptibility to infectious and non-communicable diseases. the impact of environmental and lifestyle factors on human immune function from a life science perspective. Key factors such as air pollution, climate conditions, nutrition, physical activity, sleep patterns, psychological stress, and substance use are discussed in relation to immune competence and inflammatory regulation. Evidence suggests that chronic exposure to adverse environmental conditions and unhealthy lifestyle practices can disrupt immune balance, leading to weakened host defense or exaggerated inflammatory responses. the interaction between environmental exposures, lifestyle choices, and immune function is essential for developing effective preventive and public health strategies. The importance of healthy living environments and positive lifestyle modifications in supporting optimal immune responses and reducing disease risk. Integrating environmental and lifestyle considerations into immune health research may contribute to improved disease prevention and overall human well-being.

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